Case Study Discussion Paper
The physical reaction of the body’s defensive mechanisms to illness or injury is one of the adaptive responses. As a healthcare provider, one ought to be capable of detecting clinical symptoms that suggest an imbalance in the body’s homeostasis in order to accurately diagnose and treat illnesses. This paper seeks to delve into the clinical symptoms of an illness, genes that enhance disease development, and the process of immunosuppression in the given scenario Case Study Discussion Paper.
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Presentation of Symptoms
The client’s details indicate the clinical manifestations of cellulitis of the leg. This is a serious bacterial infection that affects the skin’s dermal and subcutaneous layers. It causes pain, redness, a feeling of warmth in the affected area, and swollen skin as symptoms. It is triggered mostly by streptococci bacteria, which enter the body via a break in the skin and settles in one location. The infection happened in the scenario due to a breach that allowed bacteria to invade (Manning et al., 2019). The warmth and swelling are the consequence of a failure to adequately clean the area, which allowed germs to create substances like histamine. Inflammatory reactions were also triggered by the body’s attempt to combat the intruding bacteria.
Genes Associated with the Development of Disease
Bacteria are unable to penetrate deeply into the skin because the skin tissues are firmly packed together. The existence of keratin in the skin also aids in the prevention of bacterial invasion by depriving it of water. When the skin breaches, nevertheless, the body produces chemokines and mast cells as a defensive reaction to notify other cells engaged in the defensive system of the invading pathogens. These cells also release substances like histamine, which stimulates the blood vessels in the tissues to release fluid, resulting in swelling (Brindle and Davies, 2016). To swallow up the microorganism, phagocytic cells like monocytes and neutrophils are generated. The inflammatory reaction, which is marked by swelling, pain, warmth, and redness aids in the eradication of pathogens by attracting cells to the wounded area Case Study Discussion Paper.
Process of Immunosuppression and its Effects on the Body
Memory cells in the immune system respond in the event of a subsequent infection. Immunosuppression has an impact on the body since it lowers the body’s ability to resist illness and invasive microorganisms. Immune system elements like antibodies, phagocytes, lymphocytes, and erythrocytes, as well as complement proteins, are all compromised by immunosuppression. Immunocompromised individuals are more vulnerable to pathogens and are more prone to acquire systemic symptoms. Because of a weakened immune response, immunocompromised people with cellulitis are more prone to merely develop symptoms like warmth and, in extreme situations, pain ((Ushiyama et al., 2018). They are also less inclined to recognize the infection and, as a result, are less prone to pursue medical help, leading to the progression of systemic symptoms. Leukocytosis, fever, and bacteremia, and are common systemic symptoms in immunocompromised individuals. Cellulitis also commonly recur in immunocompromised people, necessitating prompt detection to avert consequences.
Conclusion
Cellulitis can be avoided by cleaning wounds, practicing excellent hand hygiene, and treating any sores as soon as possible. This aims to mitigate the illness from progressing and causing serious problems. It is also critical to seek medical help in order to acquire an accurate diagnosis and management.
A 42-year-old man comes to clinic with chief complaint of pain, redness, and swelling of his right calf. He states that he had been working in his yard using a string trimmer when the trimmer slipped and cut his leg. He cleaned the wound with water from the garden hose and covered the wound with a large Band-Aid. Several days later, he developed fever to 100.6˚ F and chills and noticed that his leg was swollen and red. He comes to the emergency department for definitive care. Explain why you think the patient presented the symptoms described. Identify the genes that may be associated with the development of the disease. Explain the process of immunosuppression and the effect it has on body systems Case Study Discussion Paper.
References
Brindle, R., & Davies, P. (2016). Procalcitonin and cellulitis: Cohort study of the correlation of Procalcitonin blood levels with the severity and outcome in patients with limb cellulitis. Open Forum Infectious Diseases, 3(suppl_1). https://doi.org/10.1093/ofid/ofw172.98
Manning, L., Cannon, J., Dyer, J., & Carapetis, J. (2019). Seasonal and regional patterns of lower leg cellulitis in Western Australia. Internal Medicine Journal, 49(2), 212-216. https://doi.org/10.1111/imj.14034
Ushiyama, A., Kojima, A., Yamashita, I., Naka, S., Hino, K., & Nomura, N. (2018). Status of implementation of compression therapy and incidence of cellulitis in patients with lymphedema in the upper or lower limbs. The Journal of Japanese Society of Limb Salvage and Podiatric Medicine, 10(1), 66-73. https://doi.org/10.7792/jlspm.10.66 Case Study Discussion Paper