Advanced Pharmacology Essay Assignment Paper

Explain the circumstances under which children should be prescribed drugs for off-label use

As the overwhelming number of drugs currently lack information on pediatric labeling, off-label drug use poses a serious public health challenge for children. The role of off-label use is to assist the specific patient. There are some circumstances under which off-label drugs could be administered to children. An instance could be during an emergency situation where a child has had an accident, and urgent medical attention is needed to save the life of the child (Tefera et al., 2017). The healthcare professional can also prescribe an off-label drug to help a child before proper hospital care is administered. This often happens during surgery when something unusual is noticed and could be treated with off-label medication Advanced Pharmacology Essay Assignment Paper.

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Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.

Calculating the dose from an adult’s prescription dosage is one of the strategies used to enhance safety for children from infancy to adolescence (Dooms, & Killick, 2017). The dose is calculated by age to evaluate the correct dosage for each age and deal with the situation at hand. Off-label medications that need special care and consideration used in pediatric patients include chronic illness medicines such as cancer drugs and antidepressants.

Another strategy is to have all medications clearly labeled on the correct dosage of every age. This is an efficient approach that will aim to eradicate perceptions that have been imposed for a long time (Mei et al., 2019). For example, the manufacturing firm of cancer medications should establish the proper dosage that will be appropriate for children depending on their age along with projected outcomes. This is essential because, despite being of the same age, children usually react differently to medications (Dooms & Killick, 2017). With the predicted response and effects, medical practitioners can quickly identify adverse effects on children after taking off-label medications and find ways to reverse things before they get severe Advanced Pharmacology Essay Assignment Paper.

References

Dooms, M., & Killick, J. (2017). Off-label use of medicines: The need for good practice guidelines. International Journal of Risk & Safety in Medicine29(1-2), 17-23.

Mei, M., Xu, H., Wang, L., Huang, G., Gui, Y., & Zhang, X. (2019). Current practice and awareness of pediatric off-label drug use in Shanghai, China-a questionnaire-based study. BMC pediatrics19(1), 281.

Tefera, Y. G., Gebresillassie, B. M., Mekuria, A. B., Abebe, T. B., Erku, D. A., Seid, N., & Beshir, H. B. (2017). Off‐label drug use in hospitalized children: a prospective observational study at Gondar University Referral Hospital, Northwestern Ethiopia. Pharmacology research & perspectives5(2), e00304.

Write a 1-page narrative in APA format that addresses the following: Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples. Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics Advanced Pharmacology Essay Assignment Paper