Neuronal Dysfunction in Neuropathic Pain

The paper “Neuronal Dysfunction in Neuropathic Pain” is an outstanding example of an essay on medical science.   Neuronal dysfunction is a condition that is associated with the failure of neurons to transmit impulses as expected. Usually, problems within the nervous system result in pain that is felt along the nerves also known as neuropathic pain. However, neuronal dysfunction is not the only cause of neuropathic pain as there are several other causes of this form of pain. This essay is vital as it will evaluate other sources of neuropathic pain as a way of ruling out neuronal dysfunction as the only source. Neuronal Dysfunction in Neuropathic Pain

Consequently, there are some possible problems that are likely to be encountered in the course of compiling the essay for instance lack of sufficient evidence to support the thesis. Neuronal dysfunction Neuronal dysfunction refers to the failure of neurons to carry out their daily duties as required due to problems emanating from outside or inside the body. Some neurons have the ability to regenerate although some lack this feature hence any interference results in permanent damage. Neuronal dysfunction usually leads to poor transmission of information inside the body which in turn causes considerable pain to the individual.

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However, in most cases, patients or individuals suffering from this pain cannot locate its origin hence they fail to provide accurate details of the problem (Kandel, Schwartz & Jessell, 2000). In addition to these details about neuronal dysfunction, it is apparent that neuropathic pain is not all about failure or problems with the nerves as there are several other causes of neuropathic pain that do not directly relate to abnormalities of the neurons. The other causes of neuropathic pain other than neuronal dysfunction are described below. Neuropathic pain Neuropathic pain, on the other hand, is brought about by the presence of open wounds or injuries in the central or peripheral nervous system. Neuronal Dysfunction in Neuropathic Pain

Such lesions are often brought about by excessive pressure exerted by internal or external stimuli. Consequently, the nervous system is damaged and information cannot be transmitted normally hence plenty of pain is felt. Similarly, disorders of the nervous system may bring about problems that culminate in neuropathic pain (Lee, 2000). Neuropathic pain often presents itself in various ways, for instance, it could be a continuous sharp pain spontaneous pain being felt at certain times only.

The intensity of the pain also varies considerably with some people experiencing numbness while for others the pain is excruciating (Torrance, 2006). Causes of neuropathic pain One of the reasons behind pain in the neuropathic system is dietary deficiencies, especially where essential minerals are not supplied in the diet. For instance, calcium absorption is enhanced by the presence of phosphorus in the body such that insufficient phosphorus may in the deposition of calcium stones along the axons on nerves.  Neuronal Dysfunction in Neuropathic Pain