NURS 6512 Week 4 : Skin Abnormality
People who are fair or have a weak eyesight are more likely to develop skin cancer. People may develop skin cancer in certain weather conditions or areas. For example, people living in a warm climate have a higher chance of developing skin cancer because the sun releases higher levels of radiation. Skin cancer does not occur only by exposure to ultraviolet radiation for a long time. Your family’s medical history may make you more susceptible to cancer. What are the symptoms of skin cancer?NURS 6512 Week 4 : Skin Abnormality
Skin cells that lose growth and division are called skin cancers. Another name for skin cancer is neoplasia. Skin cancer occurs from the outer layer of the skin called the epidermis and is the most common form of human cancer. Every skin cancer is important, but the most common are basal cell carcinoma, squamous cell carcinoma, melanoma. These skin cancers occur when the skin begins to grow abnormal skin cells and forms a mass called a skin tumor. – Cancer is one of the most important diseases categories in the world. Even in society like American medicine and technology development, we are still affected by cancer. According to experts from the American Cancer Society, cancer incidence rates in the American Cancer Therapy Center and the National Cancer Institute are decreasing.
Skin cancer – skin cancer occurs from epidermal cells of the skin. It is common for those who are overly exposed to the sun. According to the Skin Cancer Foundation, more than 3.3 million people in the United States receive treatment for non melanoma skin cancer every year. One in five Americans will develop skin cancer in their lifetime. The most common skin cancers are basal cell carcinoma and squamous cell carcinoma, and the most lethal skin cancer is malignant melanoma. Wart – harmless skin growth, most common hands, feet, face. Warts are caused by viruses and vary with the situation. They can be smooth, flat, rough, convex, black, small, and / or large. Remove the wart by medication at the storefront, surgery, laser, freezing or burning
I have researched many different Web-cites and articles to try and determine what role genetics plays in skin cancer.Yes there are certain genetic mutations that are inherited, or passed through the germ-line, but the main cause of skin cancer is UV radiation which is an environmental genetic defect.Many cancers begin when one or more genes in a cell are mutated, creating an abnormal protein or no protein at all.
The information provided by an abnormal protein is different from that of a normal protein, which can cause cells to multiply uncontrollably and become cancerous.
CDKN2A- mutations in this regulator of cell division are the most common causes of inherited melanoma. They are however still very uncommon overall and can appear in non-inherited cases. People who have this often have a large number of irregularly shaped moles and are often diagnosed at a relatively young age. The MC1R gene provides instructions for making a protein called the melanocortin 1 receptor. The receptor is primarily located on the surface of melanocytes, which are specialized cells that produce a pigment called melanin. Melanin is the substance that gives skin, hair and eyes their color. NURS 6512 Week 4 : Skin Abnormality
Melanocytes makes two forms of melanin, Eumelanin and Pheomelanin. The amounts of these two pigments help determine the hair color and skin usually the more Eumelanin the darker the hair and skin, also will tan easily. It also protects the skin from UV radiation in the sunlight. The more Pheomelanin the hair is red or blonde, freckles, and light skin that tans poorly, because it does not protect the skin. Which puts them at risk for skin cancer. Many changes in the MC1R gene increase the risk of developing skin cancer, including a common, serious form of skin cancer that begins in melomcytes.
Skin damage caused by UV radiation from the sun is a major risk factor for developing melanoma and other forms of skin cancer. These gene mutations germ-lines are passed from parent to child through the MC1R gene but UV radiation is the highest risk factor for getting skin cancer, and the most common in the most common in skin cancers. People who are genetically susceptible to skin cancer should avoid prolong exposure to the UV radiation from sun light, wear sun screen, and enough protective clothing when outside.NURS 6512 Week 4 : Skin Abnormality