Pathophysiology Of Benign Prostate Hyperplasia Discussion
Benign Prostrate Hyperplasia (BPH) Pathophysiology of Benign Prostate Hyperplasia • The relation of BPH to aging in men- Early symptoms may begin to show in men who are 30-50 years old. • An increased level of activity for the aromatase and five alpha-reductase enzymes • The decrease of testosterone but, on the other hand, an increase in estrogen and dihydrotestosterone. Various changes occur in patients having BPH. It is important to note that the riskiness of exposure to the condition happens with age. As men continue to age, there is an increased level of activity for the enzyme aromatase and five alpha-reductase. Pathophysiology Of Benign Prostate Hyperplasia Discussion
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The function of these enzymes is the conversion of androgen hormones into estrogen and dihydrotestosterone (Madersbachera et al., 2019). The consequence of this is a decrease in testosterone. Pathophysiology of Benign Prostate Hyperplasia • The enlargement of glandular epithelial and stromal cells • Hyperplasia of the median and lateral lobes • The occurrence or observation of most of the growth in the conversion zone of the prostate and the involvement of the peripheral area. After the decrease in testosterone, the glandular epithelial and the stromal cells will typically enlarge. Here, it is essential to note that these cells will also include the muscular fibers but exclude the anterior lobe (Madersbachera et al., 2019). There is also the enlargement of the median and lateral nodes, which can be viewed from the anatomical point of view. Pathophysiology Of Benign Prostate Hyperplasia Discussion